The organization was established in 1999 and registered in November 2000 under the Non-governmental organizations registration Statute 1998. It was incorporated on 14th December 2007, under the Companies act, Laws of Uganda as a public limited Company. PROBICOU is currently the NGO focal point organization for Strategic Approach to International Chemicals Management (SAICM) in Uganda, a member of National Steering committee on POPs in Uganda and a member of National Steering committee on Elimination of child Labor.
The organization is also accredited by Global Environment Facility and is a partner to UNEP on a number mercury partnership area, such as mercury waste and mercury in products. The organization has three: - program areas;-Biodiversity Conservation and Extractive Resources, waste and chemicals management.
The organizations subscribes to a number of international networks such as: - International POPs Elimination Network (IPEN), Zero mercury Working Group, PCIA (Partnership for Clean indoor Air), GAIA (Global Alliance for Incinerator Alternatives), PCLG (Poverty and Conservation Learning Group), Health Care without Harm Washington DC, Uganda Forestry Working Group, Member of National Steering committee on POPs in Uganda, Member of Network of Sound management of chemicals (NESMAC- Uganda), and Civil society coalition on oil and gas (CISCO) Etc.